Best Brush Killer 2022 – Reviews & Buyer’s Guide

Are you tired of having unsightly areas in your yard because they are overgrown with brush and weeds? It does not have to be that way.


Maybe you are unaware that the best brush killer products work fast and have a long lasting residual effect. The areas where you apply them will stay clear for months if these products are applied correctly.

In this article, we will take a look at five of the top specialty herbicides that work well on heavy brush and we will also tell you a little more about what to look for when shopping for them.

**Below, you'll find more detailed reviews, but you can also click links above to check current prices and read customer's reviews on Amazon.

Reviews of the Best Brush Killer Products

After doing our research here is what we feel are the best brush killer products in the lawn and garden marketplace:

Southern Ag Crossbow Specialty Weed & Brush Killer


This is an exceptional brush killing product. It will effectively kill most perennial broadleaves, a wide variety of woody plants and all different types of problem brush. Its killing power will even reach deep down into the roots of that nuisance brush growing on your landscape.

Southern Ag Crossbow Brush Killer is also one of the few products you can use that will not kill the grass in your yard. That takes a lot of the worry away when you go to apply it. This brush killer is reasonably safe to apply to your landscape even if you have pets or children (dangerous like all pesticides if ingested directly).

It is a broad spectrum herbicide that becomes highly rain resistant just two hours after you apply it. This one-gallon container will also produce a very high quantity of product so it’s suitable for large yards and farm use too. This gallon size container will make enough product to cover over 10,000 square feet of brush.


  • Makes a large quantity of brush killer
  • Rain resistant in just 2 hours
  • Effective down into the roots
  • Won’t harm most grasses
  • Easy to apply


  • Not safe for use around edible crops
  • Works slowly but effectively

Compare-N-Save Concentrate Grass and Weed Killer


This 41% Glyphosate solution is fast and effective when it comes to brush killing control around your home or farm. It is a concentrated brush killing that mixes up easily and this one-gallon container can make over 85 gallons of highly effective brush killing product.

If applied correctly you will usually start to see your problem brush start dying within 2 to 3 days. It not only kills the plant itself but will also destroy its roots too. It works great but it is not intended to be used as a pre-emergent herbicide.

This brush killing solution kills just about every type of plant so you have to be selective when you use it. It nicely starts to become rainproof just 2 hours after it has been applied. For best results, it needs to be applied on a fairly regular basis.


  • 41% highly effective Glyphosate solution
  • Rainproof in a little over 2 hours
  • See results in as little as 2 days
  • Makes 85 gallons of brush killing solution
  • Great along driveway and walkway edges


  • Is not selective and will kill most grasses
  • No residual effect

Roundup Poison Ivy Plus Tough Brush Killer Concentrate


Roundup is a very popular brand name when it comes to the removal of nuisance plants such as weeds, grasses and brush. If you need an area of tough to kill brush gone in a hurry this is the product for you. It often starts to work in less than 24 hours. Not only does it work fast but it also is rainproof in just over 30 minutes time.

It uses dual action ingredients to kill the problem brush it is applied to. That is how it can kill brush and other weeds so effectively. Its killing action will also go all the way down into a plant’s roots. This product is highly effective against stubborn and hard to kill waxy leaf plants such as poison ivy.

Be careful with this product where you use it because like most brush killers it is non-selective and will kill most anything it’s applied over. Roundup even offers a complete money back satisfaction guarantee with this product.


  •  Uses dual brush killing chemicals
  • Rainproof in 30 minutes
  • Get results in as little as 24 hours
  • Kills down to the roots
  • Even penetrates waxy leave plants


  • This is a non-selective brush killer
  • May need a repeat application

Bonide Products 331 Concentrate Brush Weed Killer


Here is a very good selective herbicide that is perfect for spot killing brush and weeds in your lawn. Best of all it will not harm your trees or grass. Its formula also tends to stay exactly where you spray it which is a nice quality too.

It is not the fastest acting brush killer but it does a great job and kills all the way down to the roots of the brush and weeds you spray it on. This product is very effective on over 70 varieties of brush, weeds and vines.

This 32-ounce container makes a large amount of brush killing product. It will treat over 10,000 square feet of area. You don’t have to worry much about rain with this brush killer either because it becomes rainproof in just over 1 hour.


  • Works on over 70 varieties of tough weeds and brush
  • Rainproof in 1 hour
  • Stays put where sprayed
  • Over 10,000 square feet of coverage from this concentrate
  • Great for lawn spot killing


  • Results are good but slow to happen
  • May need to repeat an application

RM43 43-Percent Glyphosate Plus Weed Preventer


Here is a very strong non-selective vegetation killer that is very effective of ridding problem areas in your yard of unwanted brush, weeds and vines. It even kills very tough brush and vines such as poison ivy and kudzu. This product is effective thanks to its powerful 43% Glyphosate solution.

The results you get with this product usually take a week to show up but the results are undeniable. It even kills the roots of any plants that it is applied to. This brush killer is rainproof in 1 hour and it even has a residual killing effect for up to 6 to 8 months.

Just a little bit of this product goes a long way too because it only takes six ounces of concentrate mixed in a gallon of water to make a very effective brush killing solution. This product is not recommended as a lawn spot weed killer.


  • Strong 43% Glyphosate solution
  • Rainproof within 2 hours
  • Works for up to 8 months
  • Results in less than 1 week
  • Kills over 150 varieties of nuisance brush and weeds


  • Non-selective it kills everything type of plant including grass
  • Not a lawn spot application product

The Key Characteristics of Brush Killing Herbicides

Here are some of the key traits of brush killing products to look for when looking to purchase them:



When you are buying any brush killer you don’t just want to shop by how much it costs but also by the quantity of product that it produces.

That $20 container of herbicide may seem cheaper than the $60 container of a similar product but if they are vastly different in their yield amount, then the $60 container may actually be the better buy.

So when you are shopping for brush killer make sure you know the yield of that product after it is mixed. More concentrated products may actually be the better buy if you take a close look at this so don’t overlook that fact.



One thing that all the products we will review have in common is a solid reputation as being effective at eliminating all different types of weeds and brush.

That is important to know since not all brush killing products work as advertised. So make sure you check out some reviews of the results that consumers have had using various herbicides.

Results time

Results Time

Different broad spectrum herbicides do their work at different rates of time. Some work in as little as 24 hours while others can take up to two weeks to kill the brush they are applied to. It is important to take notice of this when shopping for brush killers.

For instance, if you have a wedding coming up in a few days and want to quickly get rid of some unsightly areas of brush in your yard you will need to be selective because time is not on your side. You would need to purchase a weed killer that works in 24 hours as opposed to one that takes a week to see results.

Here is how long it takes the popular herbicide Glyphosate to work:




How long your herbicide keeps killing brush after it’s applied is important too. There is a lot of variation out there as far as the working life of different brush killers goes.

Some have to be applied to an area on a monthly basis and yet others will keep killing brush effectively for up to a year’s time. It’s important to know this information if you want to save yourself from work and not have to constantly be reapplying your brush killer product.



Most brush killer products are what is known as broad spectrum herbicides. That is a polite way of saying they will kill anything you put them on. So you have to be very careful when applying them and read the directions carefully when doing so.

There are too many exceptions to this rule. Some herbicides are more selective which means you can use them safely around some types of plants without killing them. You will have to read the manufacturers specs or the product label very carefully to determine this.

Here is a dramatization about how one of our type reviewed products gets rid of tough poison ivy and brush:



This is a very important and often overlooked characteristic of broad spectrum herbicides. Some you have to be very careful not to apply when rain is threatening because they will simply wash away and need to be reapplied.

So know how long it takes for any brush killer you buy to become rainproof.

Multi-application product

Single or Multi-application Product

Not all brush killer products work the same as far as how they are applied. Some take just a single application to effectively kill the brush and weeds they are applied over.

It’s also not uncommon for some herbicides to need two or three applications in order to be effective. So find this information out before purchasing so you do not have to do some extra work to kill the nuisance brush around your yard.

Brush killers are a type of product that you can buy so they are somewhat tailored to your individual needs. So take your time when shopping for them and get one that closely fits with your intended use.

Here is a little more information on how brush killing products work:

Our Favorite Brush Killing Product

It is fair to say there is not a bad brush and weed killing product on our top review list. All of them come highly recommended by people that have used them. There is though one brush killer we thought stood out among the rest and that was the Southern Ag Crossbow Specialty Weed & Brush Killer.

This is a product that has been proven to be effective by those who use it and it comes very highly rated. This is the only product on our top review list that is effective as a spot treatment for weeds and brush.

It does a great job of killing brush but can still be safely used around most grasses which is a big bonus. This product is also nearly rainproof just two short hours after being applied. It will even get down into the roots of any brush you apply it on and kill them too.

This is definitely a brush killing product you would want to consider purchasing if you do not have to kill your nuisance brush growth in a hurry.

About the Author Laura Bennett

Hello, I’m Laura Bennett. I love nature especially when it comes to flowers and different kinds of plants. I started a very small garden behind my house and I named it Humid Garden. So, I created this blog to provide aspiring and inspiring thoughts about gardening for gardeners and anyone who has the intention of keeping a garden.

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